In the early 22nd century, the world is recovering from the Chaos Wars—the bloody AI revolt that left millions dead and the planet in disarray. From the ashes of this conflict emerges a revitalized Vatican, with war hero Pope Gregory XIX leading the way.

Now Vatican scientists have detected a mysterious Signal from deep space which does not appear to be natural. To investigate, the pope commissions the Stella Maris, the first ship capable of traveling faster than light and going beyond our solar system. Captained by Chaos Wars veteran Dominic Rourke, the crew of the Stella Maris will face many trials and have their most fundamental beliefs challenged in order to solve the mystery of the Signal.